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Diclofenac: Influence of the Pharmaceutical Form and Wastewater Treatment on the Discharge into the Environment

Bar chart comparing the environmental impact of different Diclofenac pharmaceutical forms (transdermal patch, tablet, gel, and gel with wiped hands) and wastewater treatment levels (tertiary and quaternary). The chart illustrates the distribution of Diclofenac in the body, household waste, sewage sludge, filter residue, and water bodies. Key data emphasizes the influence of pharmaceutical form and wastewater treatment on environmental discharge.

CC-BY 4.0 German Environment Agency, CAU Kiel, Ecologic Institute, 2024

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Diclofenac: Influence of the Pharmaceutical Form and Wastewater Treatment on the Discharge into the Environment

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German Environment Agency 2023: Diclofenac: Influence of the Pharmaceutical Form and Wastewater Treatment on the Discharge into the Environment. Online: uba.de/hmp

The analgesic and anti-inflammatory pharmaceutical active ingredient Diclofenac can be administered in various forms of application. The discharge of the active ingredient into wastewater varies depending on the form of application. The final entry into the environment's water bodies is additionally influenced by the type of wastewater treatment.

Diclofenac and its Environmental Impact: Comparison of Application Forms

This infographic uses a color-coded comparative bar chart to illustrate where the active ingredient Diclofenac ultimately ends up for the application forms: patch, tablet, gel, and gel with wiped hands. How much is metabolized by the body? How much is disposed of via household waste? What impact does wiping hands after applying gel and before washing them have? How much remains in the sewage sludge of a wastewater treatment plant with tertiary treatment? How much is retained in the filter residue of a treatment plant with quaternary treatment, and how much eventually ends up in water bodies through the wastewater effluent?  

The choice of application form significantly affects how much active ingredient enters the environment. This decision has direct environmental implications, and each individual can contribute to reducing environmental pollution by making informed choices.

Target Audience for the Infographic: Professionals and Educational Institutions

The infographic is aimed at medical and pharmaceutical professionals and is used in the teaching materials developed within the project for university education, further training, and vocational schools. An additional tabular overview provides the data values and sources underlying the bar chart.

The infographic is part of the UBA portal "Human Pharmaceuticals and the Environment". With its CC-BY 4.0 license, it can be shared and modified, provided the author is credited. We encourage you to share this important information with others to raise awareness of the environmentally conscious use of pharmaceuticals.

The choice of Diclofenac's application form has significant impacts on environmental pollution. Wastewater treatment technologies also determine how much pharmaceutical residue enters the environment.

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Languages
German
English
Authorship
Clemens Woitaske-Proske
Credits

Concept and content: Melanie Kemper, Clemens Woitaske-Proske
Design and Layout: Lena Aebli

Funding
Published in
UBA online platform "Humanarzneimittel und Umwelt"
Year
Project
Project ID
Keywords
Diclofenac, application form, wastewater, wastewater treatment plant, 4th treatment stage, environmental impact, water bodies, entry, human pharmaceuticals, doctor, physician, pharmacist, pharmaceutical scientist, pharmacy, medicine
Germany
online platform, infographic, information, internet, online, portal, information material, communication, information product, online platform, visualization